Sodium bicarbonate catheter lock solution reduces hemodialysis catheter loss due to catheter-related thrombosis and blood stream infection: an open-label clinical trial
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چکیده
منابع مشابه
Minocycline-EDTA lock solution prevents catheter-related bacteremia in hemodialysis.
There is growing concern about the development of antibacterial resistance with the use of antibiotics in catheter lock solutions. The use of an antibiotic that is not usually used to treat other serious infections may be an alternative that may reduce the clinical impact should resistance develop. We conducted a randomized controlled trial to compare a solution of minocycline and EDTA with the...
متن کاملPrevention of catheter-related blood stream infection: back to basics?
BACKGROUND Central venous catheter (CVC)-related infections are a substantial problem in the intensive care unit (ICU). Our infection control team initiated the routine use of antiseptic-coated (chlorhexidine-silver sulfadiazine; Chx-SS) CVCs in our adult ICUs to reduce catheter-associated (CA) and catheter-related (CR) blood stream infection (BSI) as we implemented other educational and best p...
متن کاملA novel antimicrobial and antithrombotic lock solution for hemodialysis catheters: a multi-center, controlled, randomized trial.
BACKGROUND AND PURPOSE Catheter-related bloodstream infection is the greatest threat to the safety of patients on hemodialysis. Catheter lock solutions containing heparin have been linked to an increased risk of hemorrhage and thrombocytopenia. OBJECTIVES To ascertain the safety and efficacy for prevention of catheter-related bloodstream infection and catheter loss from patency failure of a n...
متن کاملPrevention of hemodialysis catheter-related bloodstream infection using an antimicrobial lock.
Among currently available vascular access options for hemodialysis, central venous catheters show the poorest reliability, with frequent complications of thrombosis and stenosis impairing patency. The most serious problem, however, is catheter-related bloodstream infection (CRBI), which is typically a cause for removal of the catheter and protracted systemic antibiotic therapy. In our experienc...
متن کاملConcentrated Sodium Citrate (23%) for Catheter Lock.
For chronic central venous dialysis catheters, the standard method for maintaining catheter patency between treatments is to instill (lock) catheters with 5000 - 10 000 units of heparin in each lumen. Sodium citrate (citrate) is an anticoagulant with intrinsic antibacterial activity (at 20% concentration or higher). Citrate has only transient anticoagulant effects if accidentally infused to the...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2019
ISSN: 0931-0509,1460-2385
DOI: 10.1093/ndt/gfy388